Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 7/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311511 | 0.98 | KCNA5 (0.50) | KCNA5KCNH2TSHRKCNE1CYP2D6 | |
| SCHEMBL1579392 | 0.98 | KCNA5 (0.50) | KCNA5KCNH2TSHRKCNE1CYP2D6 | |
| SCHEMBL30360441 | 0.98 | KCNA5 (0.50) | KCNA5KCNH2TSHRKCNE1CYP2D6 | |
| SCHEMBL30682711 | 0.98 | KCNA5 (0.50) | KCNA5KCNH2TSHRKCNE1CYP2D6 | |
| SCHEMBL3465329 | 0.98 | KCNA5 (0.50) | KCNA5KCNH2TSHRKCNE1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6776168 | 0.96 | KCNA5 (0.49) | KCNA5KCNH2TSHRKCNE1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6081585 | 0.96 | KCNA5 (0.49) | KCNA5KCNH2TSHRKCNE1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7929348 | 0.96 | KCNA5 (0.49) | KCNA5KCNH2TSHRKCNE1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6771556 | 0.96 | KCNA5 (0.49) | KCNA5KCNH2TSHRKCNE1CYP2D6 | |
| Hypochlorous Acid SCHEMBL20677392 | 0.92 | KCNA5 (0.46) | KCNA5KCNH2TSHRKCNE1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019050-B1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK AS (DK) | 2002-03-20 | — | — | EP | disclosed |
| US-6159941-A | Use of somatostatin agonists and antagonists for treating diseases related to the eye | NOVO NORDISK A/S (DK) | 2000-12-12 | — | — | US | disclosed |
| US-6127343-A | SELECTIVE, COMPETITIVE SOMATOSTATIN RECEPTOR LIGANDS OF NONPEPTIDE ORIGIN, FOR MEDIATING THE BIOLOGICAL EFFECT OF SOMATOSTATIN AGONISTS OR ANTAGONIST | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | disclosed |
| EP-1019050-A1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK A/S (DK) | 2000-07-19 | — | — | EP | disclosed |
| EP-0912551-A1 | SOMATOSTATIN AGONISTS AND ANTAGONISTS | NOVO NORDISK A/S (DK) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998058646-A1 | USE OF SOMATOSTATIN AGONISTS AND ANTAGONISTS FOR TREATING DISEASES RELATED TO THE EYE | NOVO NORDISK A/S (DK) | 1998-12-30 | — | — | WO | disclosed |
| WO-1997043278-A1 | SOMATOSTATIN AGONISTS AND ANTAGONISTS | NOVO NORDISK A/S (DK) | 1997-11-20 | — | — | WO | disclosed |