Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20832771 | 1.00 | TDP1 (0.61) | TDP1CYP1A2GAACYP2C9PKM | |
| SCHEMBL8406844 | 1.00 | TDP1 (0.61) | TDP1CYP1A2GAACYP2C9PKM | |
| SCHEMBL11189324 | 0.91 | TDP1 (0.55) | TDP1CYP1A2GAACYP2C9PKM | |
| SCHEMBL30360621 | 0.84 | LMNA (0.53) | TDP1GAALMNATP53ADORA3 | |
| SCHEMBL28872457 | 0.84 | LMNA (0.53) | TDP1GAALMNATP53ADORA3 | |
| SCHEMBL16244402 | 0.84 | LMNA (0.53) | TDP1LMNATP53ADORA3ADORA2A | |
| SCHEMBL6507757 | 0.82 | TDP1 (0.61) | TDP1CYP1A2GAACYP2C9PKM | |
| SCHEMBL14122295 | 0.82 | TP53 (0.52) | LMNATP53ADORA3ADORA2AKMT2A | |
| SCHEMBL14121601 | 0.82 | TP53 (0.52) | LMNATP53ADORA3ADORA2AKMT2A | |
| SCHEMBL14121604 | 0.82 | TP53 (0.52) | LMNATP53ADORA3ADORA2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705060-B | Preparation method of N- (2-morpholinyl-5-trifluoromethylphenyl) -2- (3-methylphenoxy) propionamide | 华东理工大学 | 2023-04-14 | — | — | CN | claimed |
| CN-109705060-B | Preparation method of N- (2-morpholinyl-5-trifluoromethylphenyl) -2- (3-methylphenoxy) propionamide | 华东理工大学 | 2023-04-14 | — | — | CN | disclosed |