Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19812879 | 1.00 | TAAR1 (0.52) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL32670726 | 1.00 | TAAR1 (0.52) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL19812882 | 1.00 | TAAR1 (0.52) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL19812933 | 1.00 | TAAR1 (0.52) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL30360697 | 1.00 | TAAR1 (0.52) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL19812976 | 0.87 | TAAR1 (0.51) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL19813024 | 0.87 | TAAR1 (0.51) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL21451736 | 0.87 | DRD1 (0.39) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL32670585 | 0.87 | TAAR1 (0.51) | TAAR1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL30360662 | 0.87 | TAAR1 (0.51) | TAAR1ADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514761-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116283877-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110088107-B | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-04-14 | — | — | CN | disclosed |