SCHEMBL19813024

SCHEMBL19813024

CNC[C@@H]1OCCc2c(F)cccc21

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 6/20 0.51
ADRA2A P08913 1/20 0.47
ADRA2B P18089 1/20 0.47
ADRA2C P18825 1/20 0.47
ADRA1D P25100 1/20 0.47
ADRA1A P35348 1/20 0.47
ADRA1B P35368 1/20 0.47
HTR1A P08908 1/20 0.43
DRD2 P14416 1/20 0.43
HTR7 P34969 1/20 0.43
DRD1 P21728 3/20 0.39
SLC6A4 P31645 6/20 0.39
SLC6A2 P23975 5/20 0.39
CYP2D6 P10635 3/20 0.39
SLC6A3 Q01959 1/20 0.39
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19812974 1.00 TAAR1 (0.51) TAAR1ADRA2AADRA2BADRA2CADRA1D
SCHEMBL30360662 1.00 TAAR1 (0.51) TAAR1ADRA2AADRA2BADRA2CADRA1D
SCHEMBL32670585 1.00 TAAR1 (0.51) TAAR1ADRA2AADRA2BADRA2CADRA1D
SCHEMBL19812976 1.00 TAAR1 (0.51) TAAR1ADRA2AADRA2BADRA2CADRA1D
SCHEMBL30360650 1.00 TAAR1 (0.51) TAAR1ADRA2AADRA2BADRA2CADRA1D
SCHEMBL19812882 0.87 TAAR1 (0.52) TAAR1ADRA2AADRA2BADRA2CADRA1D
SCHEMBL32670726 0.87 TAAR1 (0.52) TAAR1ADRA2AADRA2BADRA2CADRA1D
SCHEMBL30360659 0.87 TAAR1 (0.52) TAAR1ADRA2AADRA2BADRA2CADRA1D
SCHEMBL19812933 0.87 TAAR1 (0.52) TAAR1ADRA2AADRA2BADRA2CADRA1D
SCHEMBL19812879 0.87 TAAR1 (0.52) TAAR1ADRA2AADRA2BADRA2CADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035381-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUMITOMO PHARMA AMERICA, INC. (US) 2026-02-05 US disclosed
US-20240409550-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUMITOMO PHARMA AMERICA, INC. (US) 2024-12-12 US disclosed
EP-4464317-A2 COMPOUNDS AND COMPOSITIONS AND USES THEREOF Sumitomo Pharma America, Inc. (US) 2024-11-20 EP disclosed
EP-3494119-B1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUMITOMO PHARMA AMERICA INC (US) 2024-09-04 EP disclosed
US-11958862-B2 Compounds and compositions and uses thereof SUMITOMO PHARMA AMERICA, INC. (US) 2024-04-16 US disclosed
CN-110088107-B Compounds, compositions and uses thereof 赛诺维信制药公司 2023-04-14 CN disclosed
US-20220340588-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUNOVION PHARMACEUTICALS INC. (US) 2022-10-27 US disclosed
US-10927124-B2 Compounds and compositions and uses thereof SUNOVION PHARMACEUTICALS INC. (US) 2021-02-23 US disclosed
US-10927124-B2 Compounds and compositions and uses thereof SUNOVION PHARMACEUTICALS INC. (US) 2021-02-23 US disclosed
US-20190308990-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUNOVION PHARMACEUTICALS INC. 2019-10-10 US disclosed
US-20190308990-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUNOVION PHARMACEUTICALS INC. 2019-10-10 US disclosed
EP-3494119-A2 COMPOUNDS AND COMPOSITIONS AND USES THEREOF Sunovion Pharmaceuticals Inc. (US) 2019-06-12 EP disclosed
US-10196403-B2 Compounds and compositions and uses thereof SUNOVION PHARMACEUTICALS INC. (US) 2019-02-05 US disclosed
US-10196403-B2 Compounds and compositions and uses thereof SUNOVION PHARMACEUTICALS INC. (US) 2019-02-05 US disclosed
US-20180030064-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUMITOMO PHARMA AMERICA, INC. 2018-02-01 US disclosed
WO-2018023072-A2 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUNOVION PHARMACEUTICALS, INC. (US) 2018-02-01 WO disclosed
US-20180030064-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUMITOMO PHARMA AMERICA, INC. 2018-02-01 US disclosed
WO-2018023072-A2 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUNOVION PHARMACEUTICALS, INC. (US) 2018-02-01 WO disclosed
US-20180030064-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUMITOMO PHARMA AMERICA, INC. 2018-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10196403-B2 Compounds and compositions and uses thereof CHAT, ACHE, MAOB TAAR1 893/4885ADRA2A 989/4885ADRA2B 997/4885
US-20240409550-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF CHAT, ACHE, MAOB TAAR1 893/4885ADRA2A 989/4885ADRA2B 997/4885
US-20260035381-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF ADH1C, HTR6, CNR1 TAAR1 97/4885ADRA2A 394/4885ADRA2B 471/4885
US-10927124-B2 Compounds and compositions and uses thereof CHAT, ACHE, MAOB TAAR1 893/4885ADRA2A 989/4885ADRA2B 997/4885
US-11958862-B2 Compounds and compositions and uses thereof CHAT, ACHE, MAOB TAAR1 893/4885ADRA2A 989/4885ADRA2B 997/4885
US-20180030064-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF CHAT, ACHE, MAOB TAAR1 893/4885ADRA2A 989/4885ADRA2B 997/4885
US-20220340588-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF CHAT, ACHE, MAOB TAAR1 893/4885ADRA2A 989/4885ADRA2B 997/4885
US-20190308990-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF CHAT, ACHE, MAOB TAAR1 893/4885ADRA2A 989/4885ADRA2B 997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.