Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482166 | 1.00 | TSHR (0.59) | TSHRALDH1A1AKR1B1PBRM1ALOX15 | |
| SCHEMBL8477925 | 0.85 | ALDH1A1 (0.55) | TSHRALDH1A1ALOX15MAPTCYP1A2 | |
| SCHEMBL8482161 | 0.84 | TSHR (0.59) | TSHRALDH1A1AKR1B1PBRM1ALOX15 | |
| SCHEMBL1035697 | 0.82 | AKR1B1 (0.74) | TSHRALDH1A1AKR1B1PBRM1ALOX15 | |
| SCHEMBL9317962 | 0.82 | TSHR (0.57) | TSHRALDH1A1AKR1B1PBRM1ALOX15 | |
| SCHEMBL3821377 | 0.82 | TSHR (0.57) | TSHRALDH1A1AKR1B1PBRM1ALOX15 | |
| SCHEMBL7644125 | 0.79 | TSHR (0.53) | TSHRALDH1A1AKR1B1PBRM1ALOX15 | |
| SCHEMBL4500755 | 0.79 | TSHR (0.53) | TSHRALDH1A1AKR1B1PBRM1ALOX15 | |
| SCHEMBL5455144 | 0.79 | ALDH1A1 (0.57) | TSHRALDH1A1AKR1B1PBRM1ALOX15 | |
| SCHEMBL11137087 | 0.79 | TSHR (0.49) | TSHRALDH1A1AKR1B1PBRM1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4464317-A2 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | Sumitomo Pharma America, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| EP-3494119-B1 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SUMITOMO PHARMA AMERICA INC (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-116514761-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116283877-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110088107-B | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-04-14 | — | — | CN | disclosed |