Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16011491 | 1.00 | FFAR4 (0.40) | FFAR4TAAR1AMY1AALDH1A1SMN1; SMN2 | |
| SCHEMBL17429675 | 0.83 | SMN1; SMN2 (0.37) | TAAR1ALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL2790749 | 0.83 | AMY1A (0.39) | FFAR4TAAR1AMY1AALDH1A1SMN1; SMN2 | |
| SCHEMBL27570578 | 0.81 | TAAR1 (0.41) | FFAR4TAAR1AMY1AALDH1A1SMN1; SMN2 | |
| SCHEMBL12311975 | 0.79 | TAAR1 (0.64) | FFAR4TAAR1CYP1A2CYP2A6 | |
| SCHEMBL698983 | 0.78 | TAAR1 (0.63) | TAAR1AMY1AALDH1A1TRPA1NPC1 | |
| SCHEMBL29710612 | 0.78 | CHEK1 (0.40) | ALDH1A1HPGDTSHRHSP90AA1L3MBTL1 | |
| SCHEMBL38658478 | 0.78 | TAAR1 (0.63) | TAAR1AMY1AALDH1A1TRPA1NPC1 | |
| SCHEMBL1569443 | 0.78 | CHEK1 (0.40) | ALDH1A1HPGDTSHRHSP90AA1L3MBTL1 | |
| SCHEMBL24376119 | 0.78 | TYR (0.40) | FFAR4TAAR1ALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925360-B | 1-heterocyclylisochromanyl compounds and analogs for the treatment of CNS disorders | 赛诺维信制药公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-116514761-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116283877-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110088107-B | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-04-14 | — | — | CN | disclosed |