Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 5/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19813012 | 1.00 | DRD1 (0.60) | DRD1KEAP1HTR2CADRA2AADRA2B | |
| SCHEMBL19813036 | 1.00 | DRD1 (0.60) | DRD1KEAP1HTR2CADRA2AADRA2B | |
| SCHEMBL30360722 | 1.00 | DRD1 (0.60) | DRD1KEAP1HTR2CADRA2AADRA2B | |
| SCHEMBL19813014 | 1.00 | DRD1 (0.60) | DRD1KEAP1HTR2CADRA2AADRA2B | |
| SCHEMBL19824986 | 0.88 | DRD1 (0.47) | DRD1KEAP1HTR2CADRA2AADRA2B | |
| SCHEMBL19812863 | 0.84 | DRD1 (0.60) | DRD1KEAP1HTR2CADRA2AADRA2B | |
| SCHEMBL19812865 | 0.84 | DRD1 (0.60) | DRD1KEAP1HTR2CADRA2AADRA2B | |
| SCHEMBL30360684 | 0.84 | DRD1 (0.60) | DRD1KEAP1HTR2CADRA2AADRA2B | |
| SCHEMBL32670726 | 0.81 | TAAR1 (0.52) | DRD1ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL19812882 | 0.81 | TAAR1 (0.52) | DRD1ADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4464317-A2 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | Sumitomo Pharma America, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| EP-3494119-B1 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SUMITOMO PHARMA AMERICA INC (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-116514761-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116283877-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110088107-B | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-04-14 | — | — | CN | disclosed |