Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 4/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | HTR2B | P41595 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19812863 | 1.00 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2BADRA2A | |
| SCHEMBL19812865 | 1.00 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2BADRA2A | |
| SCHEMBL19816147 | 0.89 | DRD1 (0.48) | DRD1KEAP1HTR2CHTR2BADRA2A | |
| SCHEMBL19816073 | 0.89 | DRD1 (0.48) | DRD1KEAP1HTR2CHTR2BADRA2A | |
| SCHEMBL19813036 | 0.84 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2BADRA2A | |
| SCHEMBL19813014 | 0.84 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2BADRA2A | |
| SCHEMBL19813012 | 0.84 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2BADRA2A | |
| SCHEMBL30360722 | 0.84 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2BADRA2A | |
| SCHEMBL30360670 | 0.84 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2BADRA2A | |
| SCHEMBL19816616 | 0.84 | DRD1 (0.42) | DRD1HTR2CHTR2BADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088107-B | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-04-14 | — | — | CN | disclosed |