Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 5/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360711 | 1.00 | TAAR1 (0.43) | TAAR1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL32670720 | 1.00 | TAAR1 (0.43) | TAAR1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL19813055 | 1.00 | TAAR1 (0.43) | TAAR1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL19813086 | 1.00 | TAAR1 (0.43) | TAAR1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL19813056 | 1.00 | TAAR1 (0.43) | TAAR1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL31071012 | 0.90 | TAAR1 (0.44) | TAAR1MTNR1AMTNR1BKEAP1DRD1 | |
| SCHEMBL19821165 | 0.83 | MTNR1A (0.46) | TAAR1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL19812782 | 0.82 | TAAR1 (0.47) | TAAR1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL19812780 | 0.82 | TAAR1 (0.47) | TAAR1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL32670725 | 0.82 | TAAR1 (0.47) | TAAR1CHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514761-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116283877-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110088107-B | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-04-14 | — | — | CN | disclosed |