Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064075 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TP53TDP1TRPA1SRD5A1 | |
| SCHEMBL12015387 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TP53TDP1TRPA1SRD5A1 | |
| SCHEMBL21382587 | 0.84 | ALDH1A1 (0.36) | ALDH1A1TP53TDP1TRPA1SRD5A1 | |
| SCHEMBL1467180 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRMAPTKDM4E | |
| SCHEMBL28356883 | 0.78 | KDM4E (0.35) | MAPTKDM4EL3MBTL1 | |
| SCHEMBL33130 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TP53TDP1TRPA1SRD5A1 | |
| SCHEMBL19831749 | 0.75 | CYP3A4 (0.47) | ALDH1A1TP53TSHRMAPTKDM4E | |
| SCHEMBL30657013 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL31122823 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TP53TDP1TRPA1SRD5A1 | |
| SCHEMBL30786494 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514761-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116283877-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110088107-B | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-04-14 | — | — | CN | disclosed |