Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT7 | O95251 | 20/20 | 0.78 |
| ▸ | KAT6A | Q92794 | 20/20 | 0.78 |
| ▸ | KAT6B | Q8WYB5 | 14/20 | 0.78 |
| ▸ | KAT5 | Q92993 | 14/20 | 0.78 |
| ▸ | KAT8 | Q9H7Z6 | 14/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27184209 | 1.00 | KAT7 (0.78) | KAT7KAT6AKAT6BKAT5KAT8 | |
| Prifetrastat SCHEMBL22802427 | 0.93 | KAT7 (0.90) | KAT7KAT6AKAT6BKAT5KAT8 | |
| Prifetrastat SCHEMBL29490368 | 0.93 | KAT7 (0.90) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30360833 | 0.91 | KAT7 (0.86) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL27184175 | 0.91 | KAT7 (0.86) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL27184206 | 0.91 | KAT7 (0.68) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30360824 | 0.91 | KAT7 (0.68) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL25561720 | 0.89 | KAT7 (0.80) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL26165855 | 0.88 | KAT7 (1.00) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL30360823 | 0.86 | KAT7 (0.73) | KAT7KAT6AKAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698175-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITOR, COMBINATIONS AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024217563-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITOR, COMBINATIONS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-10-24 | — | — | WO | disclosed |
| EP-4433474-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2024-09-25 | — | — | EP | disclosed |
| CN-118556053-A | Lysine acetyl transferase 6A (KAT 6A) inhibitor and application thereof | 英矽智能科技知识产权有限公司 | 2024-08-27 | — | — | CN | disclosed |
| WO-2023088233-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-25 | — | — | WO | disclosed |