SCHEMBL30360833

SCHEMBL30360833

COc1cccc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC(F)F)c12

nearest known ligand 0.86

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT7 O95251 20/20 0.86
KAT6A Q92794 20/20 0.86
KAT6B Q8WYB5 15/20 0.86
KAT5 Q92993 14/20 0.86
KAT8 Q9H7Z6 14/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27184175 1.00 KAT7 (0.86) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22828657 0.93 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22802418 0.92 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL27184201 0.91 KAT7 (0.73) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30360823 0.91 KAT7 (0.73) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30360863 0.91 KAT7 (0.78) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL27184209 0.91 KAT7 (0.78) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL27184162 0.89 KAT7 (0.87) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30360830 0.89 KAT7 (0.87) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL22817397 0.89 KAT7 (1.00) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698175-A1 LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITOR, COMBINATIONS AND USES THEREOF Insilico Medicine IP Limited (HK) 2026-02-25 EP disclosed
WO-2024217563-A1 LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITOR, COMBINATIONS AND USES THEREOF INSILICO MEDICINE IP LIMITED (CN) 2024-10-24 WO disclosed
EP-4433474-A1 LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF Insilico Medicine IP Limited (HK) 2024-09-25 EP disclosed
CN-118556053-A Lysine acetyl transferase 6A (KAT 6A) inhibitor and application thereof 英矽智能科技知识产权有限公司 2024-08-27 CN disclosed
WO-2023088233-A1 LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF INSILICO MEDICINE IP LIMITED (CN) 2023-05-25 WO disclosed