SCHEMBL30361237

SCHEMBL30361237

CN1/C(=C\C=C\C2=[N+](CCCCCC(=O)O)c3ccccc3C2(C)C)C(C)(C)c2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 3/20 0.60
MAPT P10636 5/20 0.50
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
HTT P42858 4/20 0.50
POLB P06746 4/20 0.50
LMNA P02545 3/20 0.50
MEN1 O00255 3/20 0.50
THRB P10828 3/20 0.50
RECQL P46063 3/20 0.50
BLM P54132 3/20 0.50
KMT2A Q03164 3/20 0.50
USP2 O75604 3/20 0.50
PKM P14618 2/20 0.50
XBP1 P17861 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
S1PR2 O95136 1/20 0.50
ALPG P10696 1/20 0.50
CRHBP P24387 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25414768 1.00 PRMT1 (0.60) PRMT1MAPTNPC1RAB9AHTT
SCHEMBL20109010 1.00 PRMT1 (0.60) PRMT1MAPTNPC1RAB9AHTT
Hydrochloric Acid SCHEMBL31475561 0.99 PRMT1 (0.59) PRMT1MAPTNPC1RAB9AHTT
Hydrochloric Acid SCHEMBL21404280 0.99 PRMT1 (0.59) PRMT1MAPTNPC1RAB9AHTT
SCHEMBL12307341 0.99 PRMT1 (0.61) PRMT1MAPTNPC1RAB9AHTT
SCHEMBL15673012 0.96 PRMT1 (0.56) PRMT1MAPTNPC1RAB9AHTT
SCHEMBL30338228 0.96 PRMT1 (0.56) PRMT1MAPTNPC1RAB9AHTT
SCHEMBL15673013 0.96 PRMT1 (0.56) PRMT1MAPTNPC1RAB9AHTT
Hydrochloric Acid SCHEMBL21404282 0.95 PRMT1 (0.55) PRMT1MAPTNPC1RAB9AHTT
SCHEMBL23317149 0.93 PRMT1 (0.57) PRMT1MAPTNPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250208137-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES CAMBRIDGE ENTERPRISE LIMITED (GB) 2025-06-26 US claimed
EP-4493273-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES Politechnika Wroclawska (PL) 2025-01-22 EP claimed
WO-2023175356-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES POLITECHNIKA WROCLAWSKA (PL) 2023-09-21 WO claimed
EP-4161497-A1 COMPOUNDS FOR THE TREATMENT OR DIAGNOSIS OF COVID-19 Politechnika Wroclawska (PL) 2023-04-12 EP claimed
US-20250208137-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES CAMBRIDGE ENTERPRISE LIMITED (GB) 2025-06-26 US disclosed
EP-4493273-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES Politechnika Wroclawska (PL) 2025-01-22 EP disclosed
WO-2023175356-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES POLITECHNIKA WROCLAWSKA (PL) 2023-09-21 WO disclosed
EP-4161497-A1 COMPOUNDS FOR THE TREATMENT OR DIAGNOSIS OF COVID-19 Politechnika Wroclawska (PL) 2023-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250208137-A1 COMPOUNDS FOR THE DETECTION AND INHIBITION OF COAGULATION PROTEASES F11, F2, F12 PRMT1 1048/4885MAPT 4500/4885NPC1 2354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.