SCHEMBL30361600

SCHEMBL30361600

FC(F)(OC(F)(F)c1cccc(Br)c1)c1cccc(Br)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA5A P35218 1/20 0.52
CA9 Q16790 1/20 0.52
KIF11 P52732 1/20 0.39
ALDH1A1 P00352 2/20 0.38
MAPK1 P28482 2/20 0.38
IDO1 P14902 2/20 0.35
AGXT P21549 2/20 0.35
PTPN1 P18031 1/20 0.35
CTSL P07711 1/20 0.35
TSHR P16473 1/20 0.34
MAOB P27338 5/20 0.33
KDM1A O60341 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23003739 1.00 CA1 (0.52) CA1CA2CA5ACA9KIF11
SCHEMBL28659306 0.85 CA1 (0.50) CA1CA2CA5ACA9KIF11
SCHEMBL4661 0.79 CA1 (0.57) CA1CA2CA5ACA9KIF11
SCHEMBL13623124 0.79 CA1 (0.57) CA1CA2CA5ACA9KIF11
SCHEMBL29824423 0.79 CA1 (0.57) CA1CA2CA5ACA9KIF11
SCHEMBL1504913 0.77 CA1 (0.55) CA1CA2CA5ACA9KIF11
SCHEMBL1504972 0.77 CA1 (0.55) CA1CA2CA5ACA9KIF11
SCHEMBL11717621 0.76 CA1 (0.46) CA1CA2CA5ACA9KIF11
SCHEMBL5349272 0.76 CA1 (0.53) CA1CA2CA5ACA9KIF11
SCHEMBL625781 0.76 CA1 (0.53) CA1CA2CA5ACA9KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115916214-A Thyromimetic agents 速通医疗公司 2023-04-04 CN disclosed