Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29824423 | 1.00 | CA1 (0.57) | CA1CA2CA5ACA9TSHR | |
| SCHEMBL1504972 | 0.98 | CA1 (0.55) | CA1CA2CA5ACA9TSHR | |
| SCHEMBL1504913 | 0.98 | CA1 (0.55) | CA1CA2CA5ACA9TSHR | |
| Hydrazine SCHEMBL28339222 | 0.93 | CA1 (0.56) | CA1CA2CA5ACA9TSHR | |
| Bicarbonate SCHEMBL28555116 | 0.88 | CES2 (0.53) | CA1CA2CA5ACA9MAPK1 | |
| SCHEMBL788600 | 0.88 | CA1 (0.61) | CA1CA2CA5ACA9TSHR | |
| Ethylamine SCHEMBL27809229 | 0.86 | CA1 (0.50) | CA1CA2CA5ACA9TSHR | |
| Phenol SCHEMBL28217089 | 0.86 | TSHR (0.46) | CA1CA2CA5ACA9TSHR | |
| SCHEMBL13623124 | 0.85 | CA1 (0.57) | CA1CA2CA5ACA9TSHR | |
| SCHEMBL9546439 | 0.82 | NPSR1 (0.53) | CA1CA2CA5ACA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1992 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119657182-A | Composite catalyst, preparation method and application thereof | 浙江巍华新材料股份有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-118619809-B | Preparation method of m-bromobenzotrifluoride | 天门楚天精细化工有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-118619809-A | Preparation method of m-bromobenzotrifluoride | 天门楚天精细化工有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-116283823-B | Synthesis method and application of dehydroabietyl B-cyclobenzothiazole-aniline and diphenylamine compound | 广西医科大学 | 2024-04-19 | — | — | CN | claimed |
| CN-114085197-B | Synthesis method of 4- (3-trifluoromethyl phenyl) -1-piperazine-ethanol, flibanserin intermediate and flibanserin | 合肥创新医药技术有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-116283823-A | Synthesis method and application of dehydroabietyl B-cyclobenzothiazole-aniline and diphenylamine compound | 广西医科大学 | 2023-06-23 | — | — | CN | claimed |
| CN-113801015-B | Method for synthesizing aromatic carboxylic acid compound by using carbon dioxide | 华南理工大学 | 2022-11-18 | — | — | CN | claimed |
| CN-114085197-A | Synthesis method of 4- (3-trifluoromethylphenyl) -1-piperazine-ethanol, flibanserin intermediate and flibanserin | 合肥创新医药技术有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-113831279-A | Synthesis method of diflufenican | 江苏禾裕泰化学有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-113801015-A | Method for synthesizing aromatic carboxylic acid compound by using carbon dioxide | 华南理工大学 | 2021-12-17 | — | — | CN | claimed |
| EP-1463737-B1 | METHOD FOR THE PRODUCTION OF GRIGNARD COMPOUNDS | GRUENENTHAL GMBH (DE) | 2005-08-10 | — | — | EP | claimed |
| CN-1605587-A | Fluorine-containing aromatic organic tetracarboxylic dianhydride and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY (CN) | 2005-04-13 | — | — | CN | claimed |
| US-20040245657-A1 | Method for the production of Grignard compounds | GRUNENTHAL GMBH (DE) | 2004-12-09 | — | — | US | claimed |
| EP-0993432-B1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL ACETOPHENONE | BAYER AG (DE) | 2002-10-09 | — | — | EP | claimed |
| US-6420608-B1 | REACTION OF VINYL ETHER OR VINYL AMIDE WITH HALOGENATED AROMATIC COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | claimed |
| EP-0993432-A1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL ACETOPHENONE | Novartis AG (CH) | 2000-04-19 | — | — | EP | claimed |
| WO-1998058895-A1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL ACETOPHENONE | NOVARTIS AG (CH) | 1998-12-30 | — | — | WO | claimed |
| US-5053541-A | Condensation of allyamine with m-bromo-trifluoromethyl benzene in presence of nickel compound or complex as catalyst; catalyst selectivity | RHONE-POULENC CHIMIE (FR) | 1991-10-01 | — | — | US | claimed |
| EP-0385835-A1 | Process for the preparation of n-allylmetatrifluoromethylanilin | RHONE-POULENC CHIMIE (FR) | 1990-09-05 | — | — | EP | claimed |
| US-4155940-A | M-Bromo-benzotrifluorides | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040245657-A1 | Method for the production of Grignard compounds | GMNN, MSH2, GRHPR | CA1 264/4885CA2 840/4885CA5A 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.