Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907971 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL30361500 | 0.98 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL23907978 | 0.98 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL23907996 | 0.88 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL23908010 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL23907980 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL23884322 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL23907989 | 0.79 | DHODH (0.54) | ALDH1A1KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL30361625 | 0.79 | DHODH (0.54) | ALDH1A1KMT2AMEN1MAPTNPSR1 | |
| SCHEMBL23907985 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916175-A | Novel 2-pyrimidinone analogs as potent antiviral agents against alphaviruses | 南方研究院 | 2023-04-04 | — | — | CN | disclosed |