Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24178288 | 1.00 | HTR6 (0.69) | HTR6SLC6A4KMT2AMEN1CYP3A4 | |
| SCHEMBL24178316 | 1.00 | HTR6 (0.69) | HTR6SLC6A4KMT2AMEN1CYP3A4 | |
| SCHEMBL23802750 | 0.98 | HTR6 (0.68) | HTR6SLC6A4KMT2AMEN1CYP3A4 | |
| SCHEMBL23802829 | 0.98 | HTR6 (0.68) | HTR6SLC6A4KMT2AMEN1CYP3A4 | |
| SCHEMBL5442336 | 0.88 | HTR6 (0.68) | HTR6SLC6A4KMT2AMEN1CYP3A4 | |
| SCHEMBL13413612 | 0.88 | HTR6 (0.68) | HTR6SLC6A4KMT2AMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL27533549 | 0.86 | HTR6 (0.68) | HTR6SLC6A4KMT2AMEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL27493748 | 0.86 | HTR6 (0.68) | HTR6SLC6A4KMT2AMEN1CYP3A4 | |
| SCHEMBL8488005 | 0.84 | TACR2 (0.56) | HTR6SLC6A4KMT2AMAPTKDM4E | |
| SCHEMBL14595062 | 0.83 | TACR2 (0.64) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916750-A | Process for preparing SERD tricyclic compounds having substituted phenyl or pyridyl moieties | 基因泰克公司 | 2023-04-04 | — | — | CN | disclosed |