Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.42 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.42 |
| ▸ | PDE4A | P27815 | 4/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28993335 | 1.00 | MAP4K4 (0.45) | MAP4K4NR1H4KDM4CKDM5AKDM2B | |
| SCHEMBL28993333 | 0.88 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DPARP15 | |
| SCHEMBL15754409 | 0.84 | KMT2A (0.50) | MAP4K4NR1H4KDM4CKDM5AKDM2B | |
| SCHEMBL28993331 | 0.82 | PDE4B (0.37) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL14799306 | 0.82 | TSHR (0.47) | MAP4K4NR1H4KDM4CKDM2BPDE4B | |
| SCHEMBL14805357 | 0.81 | PDE4B (0.48) | MAP4K4NR1H4PDE4BPDE4APDE4C | |
| SCHEMBL28034346 | 0.79 | PDE4B (0.53) | MAP4K4NR1H4PDE4BPDE4APDE4C | |
| SCHEMBL29723405 | 0.79 | CYP19A1 (0.56) | MAP4K4NR1H4PDE4BPDE4APDE4C | |
| SCHEMBL573852 | 0.79 | CYP19A1 (0.56) | MAP4K4NR1H4PDE4BPDE4APDE4C | |
| SCHEMBL17050363 | 0.78 | NR1H4 (0.48) | MAP4K4NR1H4KDM4CKDM2BPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698459-B | 1-phenyl-2-pyridylalkyl alcohol derivatives as phosphodiesterase inhibitors | 奇斯药制品公司 | 2023-05-05 | — | — | CN | disclosed |