Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.43 |
| ▸ | PDE4A | P27815 | 5/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30362004 | 0.88 | MAP4K4 (0.45) | PDE4BPDE4APDE4CPDE4DPARP15 | |
| SCHEMBL28993335 | 0.88 | MAP4K4 (0.45) | PDE4BPDE4APDE4CPDE4DPARP15 | |
| SCHEMBL15754411 | 0.86 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL15786277 | 0.85 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL28993331 | 0.84 | PDE4B (0.37) | PDE4BPDE4APDE4CPDE4DHTR4 | |
| SCHEMBL15754600 | 0.84 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL28033753 | 0.82 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL2762621 | 0.81 | HTR4 (0.52) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL2762046 | 0.81 | CYP19A1 (0.55) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL2090601 | 0.79 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698459-B | 1-phenyl-2-pyridylalkyl alcohol derivatives as phosphodiesterase inhibitors | 奇斯药制品公司 | 2023-05-05 | — | — | CN | disclosed |