Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25251320 | 1.00 | PTGDR2 (0.38) | PTGDR2MAPKAPK2NAMPTAAK1PRMT5 | |
| SCHEMBL25350925 | 0.89 | NAMPT (0.35) | PTGDR2MAPKAPK2NAMPTAAK1PRMT5 | |
| SCHEMBL30362262 | 0.89 | NAMPT (0.35) | PTGDR2MAPKAPK2NAMPTAAK1PRMT5 | |
| SCHEMBL30362298 | 0.88 | MAPKAPK2 (0.36) | PTGDR2MAPKAPK2NAMPTAAK1PRMT5 | |
| SCHEMBL25254861 | 0.88 | MAPKAPK2 (0.36) | PTGDR2MAPKAPK2NAMPTAAK1PRMT5 | |
| SCHEMBL25297826 | 0.87 | AR (0.39) | MAPKAPK2NAMPTAAK1 | |
| SCHEMBL30362342 | 0.87 | AR (0.39) | MAPKAPK2NAMPTAAK1 | |
| SCHEMBL24896779 | 0.87 | PTGDR2 (0.34) | PTGDR2MAPKAPK2NAMPTAAK1RORC | |
| SCHEMBL30192548 | 0.87 | PTGDR2 (0.34) | PTGDR2MAPKAPK2NAMPTAAK1RORC | |
| SCHEMBL25350428 | 0.87 | MAPT (0.35) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989225-A | Imidazole-pyrazole derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2023-04-18 | — | — | CN | disclosed |