Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25254861 | 1.00 | MAPKAPK2 (0.36) | MAPKAPK2AAK1PRMT5WDR77PTGDR2 | |
| SCHEMBL25251320 | 0.88 | PTGDR2 (0.38) | MAPKAPK2AAK1PRMT5WDR77PTGDR2 | |
| SCHEMBL30362248 | 0.88 | PTGDR2 (0.38) | MAPKAPK2AAK1PRMT5WDR77PTGDR2 | |
| SCHEMBL25352595 | 0.88 | UCHL1 (0.36) | — | |
| SCHEMBL30362262 | 0.86 | NAMPT (0.35) | MAPKAPK2AAK1PRMT5WDR77PTGDR2 | |
| SCHEMBL25350925 | 0.86 | NAMPT (0.35) | MAPKAPK2AAK1PRMT5WDR77PTGDR2 | |
| SCHEMBL30362342 | 0.85 | AR (0.39) | MAPKAPK2AAK1NAMPT | |
| SCHEMBL25297826 | 0.85 | AR (0.39) | MAPKAPK2AAK1NAMPT | |
| SCHEMBL25253508 | 0.81 | MAPKAPK2 (0.41) | MAPKAPK2PTGDR2MAPK14HDAC3HDAC8 | |
| SCHEMBL29004191 | 0.80 | FFAR1 (0.41) | MAPKAPK2AAK1PRMT5WDR77HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989225-A | Imidazole-pyrazole derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2023-04-18 | — | — | CN | disclosed |