Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | RAD52 | P43351 | 2/20 | 0.61 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25162622 | 1.00 | ATM (0.62) | ATMRAD52UHRF1KDM4EMAPK1 | |
| SCHEMBL30365362 | 0.90 | ATM (0.50) | ATMRAD52UHRF1KDM4EMAPK1 | |
| SCHEMBL25162497 | 0.90 | ATM (0.50) | ATMRAD52UHRF1KDM4EMAPK1 | |
| SCHEMBL25162606 | 0.90 | ATM (0.50) | ATMRAD52UHRF1KDM4EMAPK1 | |
| SCHEMBL34462300 | 0.82 | ATM (0.62) | ATMRAD52UHRF1KDM4EMAPK1 | |
| SCHEMBL5496539 | 0.81 | PDE5A (0.47) | KDM4EMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15584189 | 0.79 | KDM4E (0.44) | KDM4EMAPK1HSD17B10MEN1KMT2A | |
| SCHEMBL20697268 | 0.78 | MEN1 (0.54) | ATMRAD52UHRF1KDM4EMAPK1 | |
| SCHEMBL28542154 | 0.78 | CYP1A2 (0.54) | RAD52UHRF1KDM4EMAPK1MEN1 | |
| SCHEMBL4277553 | 0.77 | ALDH1A1 (0.45) | KDM4EMAPK1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023060904-A1 | NALIDINONE COMPOUND AS FGFR4 INHIBITOR AND USE THEREOF | 温州医科大学 | 2023-04-20 | — | — | WO | disclosed |