Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.59 |
| ▸ | HTR2B | P41595 | 12/20 | 0.58 |
| ▸ | HTR2C | P28335 | 11/20 | 0.58 |
| ▸ | HTR2A | P28223 | 9/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | MTR | Q99707 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21614132 | 1.00 | PARP1 (0.59) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL16334116 | 0.86 | HTR2B (0.67) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL16336941 | 0.86 | HTR2B (0.67) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| Hydrochloric Acid SCHEMBL16337499 | 0.85 | HTR2B (0.65) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| Hydrochloric Acid SCHEMBL16337502 | 0.85 | HTR2B (0.65) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL121288 | 0.85 | HTR2C (0.59) | PARP1HTR2BHTR2CHTR2ACRBN | |
| SCHEMBL31252793 | 0.83 | MTR (0.60) | PARP1HTR2BHTR2CHTR2ACRBN | |
| SCHEMBL2183088 | 0.83 | MTR (0.60) | PARP1HTR2BHTR2CHTR2ACRBN | |
| SCHEMBL1976916 | 0.82 | PARP1 (0.56) | PARP1HTR2BHTR2CHTR2ACRBN | |
| SCHEMBL31252751 | 0.82 | MTR (0.59) | PARP1CRBNMTRKMT2ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452945-A2 | CHEMICAL LINKERS | Sigma-Aldrich Co. LLC (US) | 2024-10-30 | — | — | EP | disclosed |
| EP-4347580-A1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND MEDICAL USES THEREOF | Novartis AG (CH) | 2024-04-10 | — | — | EP | disclosed |
| WO-2023122481-A2 | CHEMICAL LINKERS | SIGMA-ALDRICH CO. LLC (US) | 2023-06-29 | — | — | WO | disclosed |
| EP-4188549-A1 | HETEROARYL SUBSTITUTED 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2023-06-07 | — | — | EP | disclosed |