Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CDA | P32320 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366231 | 0.89 | GFER (0.46) | GFERPKMRAB9AGLATOP2A | |
| SCHEMBL16254687 | 0.86 | GFER (0.43) | GFERPKMRAB9AGLATOP2A | |
| SCHEMBL4411179 | 0.82 | PKM (0.43) | GFERPKMRAB9AGLATOP2A | |
| SCHEMBL3558395 | 0.82 | GFER (0.51) | GFERPKMRAB9AGLATOP2A | |
| SCHEMBL18627868 | 0.79 | PKM (0.54) | GFERPKMRAB9AGLATOP2A | |
| SCHEMBL1487124 | 0.79 | PKM (0.50) | GFERPKMRAB9AGLATOP2A | |
| SCHEMBL16235860 | 0.79 | PKM (0.44) | GFERPKMRAB9AGLATOP2A | |
| SCHEMBL25088614 | 0.79 | GFER (0.41) | GFERPKMRAB9AGLATOP2A | |
| SCHEMBL11956999 | 0.79 | TOP2A (0.42) | GFERPKMRAB9AGLATOP2A | |
| SCHEMBL19958521 | 0.79 | GFER (0.41) | GFERPKMRAB9AGLATOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920199-B | Piperazinone substituent or derivative thereof, preparation method and application thereof, and pharmaceutical composition | 四川大学 | 2023-02-03 | — | — | CN | disclosed |