SCHEMBL30366308

SCHEMBL30366308

C=CCN1C(=O)CN(C(=O)OC(C)(C)C)c2ccc(F)c(Br)c21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
SCN5A Q14524 1/20 0.33
SCN9A Q15858 1/20 0.33
F13A1 P00488 1/20 0.32
TGM2 P21980 1/20 0.32
TGM1 P22735 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.30
GAA P10253 2/20 0.30
HPGD P15428 2/20 0.30
TP53 P04637 1/20 0.30
ALOX15 P16050 1/20 0.30
MAPK1 P28482 1/20 0.30
GPR119 Q8TDV5 1/20 0.30
USP30 Q70CQ3 1/20 0.30
DHODH Q02127 1/20 0.30
BRD4 O60885 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21820342 1.00 HDAC1 (0.43) HDAC1HDAC6SCN5ASCN9AF13A1
SCHEMBL30366412 0.91 HDAC1 (0.44) HDAC1HDAC6SCN5ASCN9AGPR119
SCHEMBL20582330 0.91 HDAC1 (0.44) HDAC1HDAC6SCN5ASCN9AGPR119
SCHEMBL21820204 0.85 HDAC1 (0.45) HDAC1HDAC6SCN5ASCN9AGPR119
SCHEMBL30366302 0.85 HDAC1 (0.45) HDAC1HDAC6SCN5ASCN9AGPR119
SCHEMBL28980749 0.83 PTGDR2 (0.36) PTGDR2KDM4EALDH1A1GAA
SCHEMBL20582331 0.82 HDAC1 (0.43) HDAC1HDAC6SCN5ASCN9AGPR119
SCHEMBL30366038 0.82 HDAC1 (0.43) HDAC1HDAC6SCN5ASCN9AGPR119
SCHEMBL20582419 0.79 HDAC1 (0.40) HDAC1HDAC6SCN5ASCN9A
SCHEMBL30366161 0.79 HDAC1 (0.40) HDAC1HDAC6SCN5ASCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110382505-B Heterocyclic compounds useful as antibacterial agents and process for producing the same 巴格沃克斯研究有限公司 2023-04-04 CN disclosed