SCHEMBL30366038

SCHEMBL30366038

CN1C(=O)CN(C(=O)OC(C)(C)C)c2ccc(F)c(Br)c21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
CASP2 P42575 1/20 0.36
SCN5A Q14524 1/20 0.34
SCN9A Q15858 1/20 0.34
USP30 Q70CQ3 2/20 0.33
BRD4 O60885 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
GABRB2 P47870 1/20 0.32
GABRA6 Q16445 1/20 0.32
KDM1A O60341 1/20 0.32
NR1H2 P55055 1/20 0.32
GPR119 Q8TDV5 3/20 0.31
BCHE P06276 1/20 0.31
UCHL1 P09936 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20582331 1.00 HDAC1 (0.43) HDAC1HDAC6CASP2SCN5ASCN9A
SCHEMBL30366302 0.86 HDAC1 (0.45) HDAC1HDAC6CASP2SCN5ASCN9A
SCHEMBL21820204 0.86 HDAC1 (0.45) HDAC1HDAC6CASP2SCN5ASCN9A
SCHEMBL20582330 0.83 HDAC1 (0.44) HDAC1HDAC6SCN5ASCN9AUSP30
SCHEMBL30366412 0.83 HDAC1 (0.44) HDAC1HDAC6SCN5ASCN9AUSP30
SCHEMBL21820342 0.82 HDAC1 (0.43) HDAC1HDAC6SCN5ASCN9AUSP30
SCHEMBL30366308 0.82 HDAC1 (0.43) HDAC1HDAC6SCN5ASCN9AUSP30
SCHEMBL28980758 0.82 CASP2 (0.40) CASP2
SCHEMBL20582419 0.81 HDAC1 (0.40) HDAC1HDAC6SCN5ASCN9A
SCHEMBL30366161 0.81 HDAC1 (0.40) HDAC1HDAC6SCN5ASCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110382505-B Heterocyclic compounds useful as antibacterial agents and process for producing the same 巴格沃克斯研究有限公司 2023-04-04 CN disclosed