Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.43 |
| ▸ | MTOR | P42345 | 7/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445139 | 1.00 | KDM4E (0.51) | KDM4EGAAALDH1A1MAPK1TSHR | |
| SCHEMBL22234855 | 0.84 | MAPT (0.49) | KDM4EALDH1A1MAPK1TSHR | |
| SCHEMBL11224235 | 0.83 | KDM4E (0.51) | KDM4EGAAALDH1A1MAPK1PIK3CA | |
| SCHEMBL2317513 | 0.82 | CYP1A2 (0.47) | ALDH1A1MAPK1TSHR | |
| SCHEMBL14725974 | 0.81 | ALDH1A1 (0.48) | KDM4EGAAALDH1A1MAPK1TSHR | |
| SCHEMBL5560392 | 0.81 | KDM4E (0.50) | KDM4EGAAALDH1A1MAPK1TSHR | |
| SCHEMBL11219511 | 0.81 | ALDH1A1 (0.48) | KDM4EGAAALDH1A1MAPK1TSHR | |
| SCHEMBL14725971 | 0.81 | ALDH1A1 (0.44) | KDM4EGAAALDH1A1MAPK1TSHR | |
| SCHEMBL2321391 | 0.81 | MAPK1 (0.50) | KDM4EGAAALDH1A1MAPK1TSHR | |
| SCHEMBL3146942 | 0.79 | HRH4 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165045-A1 | DUAL KINASE-BROMODOMAIN INHIBITORS | Monash University (AU) | 2023-04-19 | — | — | EP | disclosed |