Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366887 | 0.91 | CYP3A4 (0.41) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL30366760 | 0.90 | RET (0.32) | RET | |
| SCHEMBL30366837 | 0.89 | ALOX5AP (0.36) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL30366506 | 0.84 | RET (0.32) | ALOX5APFEN1RET | |
| SCHEMBL28981129 | 0.82 | ALOX5AP (0.33) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL30366523 | 0.78 | KDR (0.33) | ALOX5APFEN1RET | |
| SCHEMBL30325689 | 0.77 | CYP3A4 (0.53) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL22677138 | 0.75 | CYP3A4 (0.49) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL30303789 | 0.75 | CYP3A4 (0.49) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL30325855 | 0.75 | CYP3A4 (0.53) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894481-A | Nitrogen-containing heteroaryl compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |