Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.37 |
| ▸ | FEN1 | P39748 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366459 | 0.91 | ALOX5AP (0.35) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30366760 | 0.82 | RET (0.32) | — | |
| SCHEMBL28981104 | 0.82 | ALOX5AP (0.40) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL25640020 | 0.81 | CYP3A4 (0.45) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL22678193 | 0.79 | CYP3A4 (0.42) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL29452495 | 0.79 | CYP3A4 (0.42) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30367018 | 0.79 | CYP3A4 (0.46) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30366837 | 0.79 | ALOX5AP (0.36) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL22658635 | 0.78 | CYP3A4 (0.43) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL29452469 | 0.78 | CYP3A4 (0.43) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894481-A | Nitrogen-containing heteroaryl compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |