SCHEMBL30366813

SCHEMBL30366813

FC(F)(F)c1cccc(NCc2nnc3n2CCCCC3)c1

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 3/20 0.70
▸ SMN1; SMN2 Q16637 1/20 0.70
▸ LMNA P02545 6/20 0.62
▸ SHMT2 P34897 2/20 0.61
▸ L3MBTL1 Q9Y468 2/20 0.59
▸ MAPT P10636 1/20 0.59
▸ TSHR P16473 1/20 0.59
▸ KDM4E B2RXH2 1/20 0.59
▸ TP53 P04637 2/20 0.55
▸ GFER P55789 1/20 0.52
▸ ALDH1A1 P00352 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30366790 0.86 LMNA (0.75) GAASMN1; SMN2LMNASHMT2L3MBTL1
SCHEMBL30367009 0.80 GAA (0.70) GAASMN1; SMN2LMNASHMT2L3MBTL1
SCHEMBL30366789 0.79 LMNA (0.80) GAASMN1; SMN2LMNASHMT2L3MBTL1
SCHEMBL17792898 0.76 LMNA (1.00) GAASMN1; SMN2LMNASHMT2L3MBTL1
SCHEMBL30938207 0.74 LMNA (0.64) GAASMN1; SMN2LMNASHMT2L3MBTL1
SCHEMBL30366880 0.74 LMNA (0.64) GAASMN1; SMN2LMNASHMT2L3MBTL1
SCHEMBL12857389 0.73 HPGD (0.60) GAALMNAL3MBTL1MAPTTSHR
SCHEMBL14680354 0.72 LMNA (0.60) GAASMN1; SMN2LMNAL3MBTL1MAPT
SCHEMBL30366818 0.72 LMNA (0.61) GAASMN1; SMN2LMNASHMT2L3MBTL1
SCHEMBL30938206 0.71 KDM4E (0.75) GAASMN1; SMN2LMNASHMT2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250235462-A1 NOVEL CAPSID ASSEMBLY INHIBITORS AM SCIENCES INC (KR) 2025-07-24 — — US disclosed
EP-4416150-A1 NOVEL CAPSID ASSEMBLY INHIBITORS AM Sciences Inc (KR) 2024-08-21 — — EP disclosed
WO-2023063698-A1 NOVEL CAPSID ASSEMBLY INHIBITORS AM SCIENCES INC (KR) 2023-04-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250235462-A1 NOVEL CAPSID ASSEMBLY INHIBITORS ZC3HAV1, GTF3C3, ZC3HAV1L GAA 1080/4885SMN1; SMN2 2700/4885LMNA 3018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback