Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 6/20 | 0.67 |
| ▸ | BTK | Q06187 | 3/20 | 0.63 |
| ▸ | MERTK | Q12866 | 12/20 | 0.58 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367450 | 0.87 | TYRO3 (0.81) | TYRO3MERTKAXL | |
| SCHEMBL30367412 | 0.81 | TYRO3 (0.62) | TYRO3MERTKAXL | |
| SCHEMBL29052449 | 0.81 | TYRO3 (0.62) | TYRO3MERTKAXL | |
| SCHEMBL30499557 | 0.81 | TYRO3 (0.65) | TYRO3BTKMERTKAXL | |
| SCHEMBL30367529 | 0.81 | TYRO3 (0.64) | TYRO3MERTKAXL | |
| SCHEMBL29052677 | 0.81 | TYRO3 (0.65) | TYRO3BTKMERTKAXL | |
| SCHEMBL29052857 | 0.81 | TYRO3 (0.64) | TYRO3MERTKAXL | |
| SCHEMBL30499499 | 0.81 | BTK (0.60) | TYRO3BTK | |
| SCHEMBL19398147 | 0.81 | TYRO3 (1.00) | TYRO3MERTKAXL | |
| SCHEMBL30367554 | 0.79 | TYRO3 (0.72) | TYRO3MERTKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |