Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | TOP1 | P11387 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432303 | 1.00 | FASN (0.51) | FASNPTPN1KDM4ETERTPPARG | |
| SCHEMBL432302 | 1.00 | FASN (0.51) | FASNPTPN1KDM4ETERTPPARG | |
| SCHEMBL10423108 | 1.00 | FASN (0.51) | FASNPTPN1KDM4ETERTPPARG | |
| SCHEMBL10423107 | 1.00 | FASN (0.51) | FASNPTPN1KDM4ETERTPPARG | |
| SCHEMBL18301262 | 0.93 | FASN (0.42) | FASNPTPN1KDM4ETERTPPARG | |
| SCHEMBL18301263 | 0.93 | FASN (0.42) | FASNPTPN1KDM4ETERTPPARG | |
| SCHEMBL432723 | 0.87 | PTPN1 (0.53) | FASNPTPN1TERTPPARGPPARD | |
| SCHEMBL432724 | 0.87 | PTPN1 (0.53) | FASNPTPN1TERTPPARGPPARD | |
| SCHEMBL429510 | 0.86 | FAAH (0.49) | FASNPTPN1KDM4EMAPTBLM | |
| SCHEMBL429511 | 0.86 | FAAH (0.49) | FASNPTPN1KDM4EMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082360-A | Polycyclic compounds as SOS1 inhibitors | 昆药集团股份有限公司 | 2023-05-09 | — | — | CN | disclosed |