Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983374 | 0.83 | MAPT (0.49) | ALDH1A1KDM4EMAPTTDP1CYP2D6 | |
| SCHEMBL10491992 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTTDP1CYP2D6 | |
| SCHEMBL18312558 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTTDP1CYP2D6 | |
| SCHEMBL1592876 | 0.81 | TDP1 (0.60) | ALDH1A1KDM4EMAPTTDP1CYP2D6 | |
| SCHEMBL25433146 | 0.79 | CYP2D6 (0.50) | ALDH1A1KDM4EMAPTTDP1CYP2D6 | |
| SCHEMBL1710110 | 0.78 | TDP1 (0.53) | ALDH1A1KDM4EMAPTTDP1CYP2D6 | |
| SCHEMBL30206812 | 0.77 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTTDP1CYP2D6 | |
| SCHEMBL11129324 | 0.77 | TDP1 (0.49) | ALDH1A1KDM4EMAPTTDP1CYP2D6 | |
| SCHEMBL1710099 | 0.77 | TDP1 (0.51) | ALDH1A1KDM4EMAPTTDP1CYP2D6 | |
| SCHEMBL21169162 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTTDP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612294-B | Human cerebulin ligands and bifunctional compounds comprising same | 阿尔维纳斯运营股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-115974840-A | Human cereblon ligand and bifunctional compound comprising same | 阿尔维纳斯运营股份有限公司 | 2023-04-18 | — | — | CN | disclosed |