Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 12/20 | 0.60 |
| ▸ | BTK | Q06187 | 4/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | TEC | P42680 | 2/20 | 0.43 |
| ▸ | TXK | P42681 | 2/20 | 0.43 |
| ▸ | BMX | P51813 | 2/20 | 0.43 |
| ▸ | ITK | Q08881 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29721103 | 0.77 | BTK (0.73) | TNK2BTK | |
| SCHEMBL4361853 | 0.75 | TNK2 (1.00) | TNK2BTK | |
| SCHEMBL399045 | 0.73 | IGF1R (0.62) | TNK2EGFR | |
| SCHEMBL6940080 | 0.70 | RAF1 (0.67) | TNK2BTKEGFR | |
| SCHEMBL27678612 | 0.70 | IGF1R (0.59) | TNK2EGFR | |
| SCHEMBL13504841 | 0.69 | TNK2 (0.78) | TNK2BTK | |
| SCHEMBL11980652 | 0.69 | RAF1 (0.54) | TNK2EGFR | |
| SCHEMBL6942526 | 0.68 | PIK3CA (0.55) | TNK2BTKEGFR | |
| SCHEMBL3897506 | 0.68 | IGF1R (0.57) | TNK2EGFR | |
| SCHEMBL30367439 | 0.67 | BTK (0.50) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |