Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19064516 | 0.87 | KDM4E (0.43) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL6069780 | 0.86 | KDM4E (0.49) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL29524852 | 0.86 | KDM4E (0.52) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL31013216 | 0.85 | KDM4E (0.63) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL726909 | 0.83 | KDM4E (0.46) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL15361966 | 0.82 | MAPT (0.47) | KDM4EHPGDALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11179021 | 0.81 | KDM4E (0.50) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL4552093 | 0.81 | ERCC5 (0.45) | HPGDSMN1; SMN2TSHRKMT2AGABBR2 | |
| SCHEMBL8411463 | 0.80 | KDM4E (0.48) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL10824784 | 0.80 | KDM4E (0.48) | KDM4EHPGDALDH1A1SMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600797-A | Composition comprising tetrahydrocannabinol for the treatment of acute respiratory failure and/or acute respiratory distress syndrome | A·N·纳吉 | 2023-08-15 | — | — | CN | disclosed |
| CN-109879839-B | 6-piperazinemethyl-7-hydroxy benzofuran compound and medical application thereof | 沈阳大学 | 2023-04-25 | — | — | CN | disclosed |