Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 10/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23887735 | 1.00 | FFAR1 (0.39) | FFAR1DPP4TRPV3GRIN2BFFAR4 | |
| SCHEMBL23887874 | 0.90 | TRPV3 (0.36) | FFAR1TRPV3 | |
| SCHEMBL23887730 | 0.88 | DPP4 (0.40) | DPP4 | |
| SCHEMBL30367959 | 0.88 | DPP4 (0.40) | DPP4 | |
| SCHEMBL23895835 | 0.87 | TRPV3 (0.36) | FFAR1TRPV3GRIN2B | |
| SCHEMBL23895850 | 0.87 | TRPV3 (0.35) | FFAR1TRPV3GRIN2BFFAR4 | |
| SCHEMBL23895839 | 0.87 | TRPV3 (0.35) | FFAR1TRPV3GRIN2BFFAR4 | |
| SCHEMBL23887836 | 0.82 | TOP1 (0.39) | FFAR1GRIN2BFFAR4 | |
| SCHEMBL23896266 | 0.82 | DPP4 (0.38) | FFAR1DPP4 | |
| SCHEMBL23895764 | 0.82 | FFAR1 (0.37) | FFAR1DPP4TRPV3GRIN2BFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697969-A | 7-or 8-hydroxy-isoquinoline and 7-or 8-hydroxy-quinoline derivatives as alpha-1 antitrypsin modulators for the treatment of alpha-1 antitrypsin deficiency (AATD) | 弗特克斯药品有限公司 | 2023-02-03 | — | — | CN | disclosed |