SCHEMBL303674

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3376406	0.95	SIRT2 (0.44)	SIRT2CNR1CNR2NR1H2MEN1
	SCHEMBL303335	0.91	NR1H2 (0.45)	SIRT2CNR1CNR2NR1H2MEN1
	SCHEMBL302683	0.86	KCNA5 (0.39)	SIRT2CNR1CNR2NR1H2MEN1
	SCHEMBL302783	0.85	SIRT2 (0.45)	SIRT2CNR1CNR2NR1H2MEN1
	SCHEMBL303336	0.84	NR1H2 (0.45)	SIRT2CNR1CNR2NR1H2MEN1
	SCHEMBL2186792	0.84	SIRT2 (0.45)	SIRT2CNR1CNR2NR1H2MEN1
	SCHEMBL3377129	0.83	MEN1 (0.55)	SIRT2CNR1CNR2NR1H2MEN1
	SCHEMBL2322870	0.83	MEN1 (0.42)	SIRT2CNR1CNR2NR1H2MEN1
	SCHEMBL3380436	0.83	NR1H2 (0.45)	NR1H2MEN1KMT2ARORCKAT6A
	SCHEMBL3380912	0.83	SIRT2 (0.45)	SIRT2CNR1CNR2NR1H2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.