Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 5/20 | 0.43 |
| ▸ | MERTK | Q12866 | 6/20 | 0.37 |
| ▸ | AXL | P30530 | 10/20 | 0.37 |
| ▸ | MET | P08581 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29052497 | 0.90 | TYRO3 (0.52) | TYRO3MERTKAXL | |
| SCHEMBL30499514 | 0.85 | POLB (0.33) | — | |
| SCHEMBL30367257 | 0.84 | TYRO3 (0.49) | TYRO3MERTK | |
| SCHEMBL30367391 | 0.75 | PDE9A (0.38) | — | |
| SCHEMBL30367412 | 0.73 | TYRO3 (0.62) | TYRO3MERTKAXL | |
| SCHEMBL29052449 | 0.73 | TYRO3 (0.62) | TYRO3MERTKAXL | |
| SCHEMBL21903780 | 0.71 | BTK (0.46) | — | |
| SCHEMBL21903774 | 0.71 | BTK (0.46) | — | |
| SCHEMBL30499566 | 0.70 | TYRO3 (0.35) | TYRO3MERTK | |
| SCHEMBL31684327 | 0.70 | BTK (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |