Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 6/20 | 0.52 |
| ▸ | MERTK | Q12866 | 14/20 | 0.45 |
| ▸ | AXL | P30530 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367531 | 0.90 | TYRO3 (0.43) | TYRO3MERTKAXL | |
| SCHEMBL29052449 | 0.84 | TYRO3 (0.62) | TYRO3MERTKAXL | |
| SCHEMBL30367412 | 0.84 | TYRO3 (0.62) | TYRO3MERTKAXL | |
| SCHEMBL30499571 | 0.80 | EGFR (0.40) | — | |
| SCHEMBL30499566 | 0.79 | TYRO3 (0.35) | TYRO3MERTK | |
| SCHEMBL30367548 | 0.76 | TYRO3 (0.57) | TYRO3MERTKAXL | |
| SCHEMBL29052450 | 0.76 | TYRO3 (0.57) | TYRO3MERTKAXL | |
| SCHEMBL30367690 | 0.76 | KMT2A (0.41) | — | |
| SCHEMBL21903780 | 0.76 | BTK (0.46) | — | |
| SCHEMBL21903774 | 0.76 | BTK (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |