Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.63 |
| ▸ | ACP1 | P24666 | 1/20 | 0.61 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.57 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29566096 | 0.79 | EHMT2 (0.70) | ACP1EHMT2EHMT1 | |
| SCHEMBL29565764 | 0.78 | EHMT2 (0.57) | ACP1EHMT2EHMT1CYP2D6CYP2C19 | |
| SCHEMBL2952575 | 0.77 | TLR8 (1.00) | TLR8CYP2C19 | |
| SCHEMBL23412112 | 0.77 | TLR8 (0.74) | TLR8 | |
| SCHEMBL23412189 | 0.77 | TLR8 (0.74) | TLR8 | |
| SCHEMBL10809994 | 0.76 | HRH3 (0.64) | HRH3 | |
| SCHEMBL16836385 | 0.76 | TLR8 (1.00) | TLR8 | |
| SCHEMBL16836411 | 0.76 | TLR8 (1.00) | TLR8 | |
| SCHEMBL28825618 | 0.75 | TLR8 (0.56) | TLR8EHMT2EHMT1CYP2C19HRH3 | |
| SCHEMBL16836294 | 0.75 | TLR8 (1.00) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442947-B1 | AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS AS EHMT1 AND EHMT2 INHIBITORS | EPIZYME INC (US) | 2023-06-07 | — | — | EP | disclosed |