Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.57 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ACP1 | P24666 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29566096 | 0.87 | EHMT2 (0.70) | EHMT2EHMT1ACP1 | |
| SCHEMBL10809994 | 0.80 | HRH3 (0.64) | HRH3 | |
| SCHEMBL19260628 | 0.80 | ACP1 (0.55) | EHMT2CYP2D6CYP2C19ACP1SRC | |
| Hydrochloric Acid SCHEMBL10815844 | 0.78 | HRH3 (0.64) | HRH3KDM4EL3MBTL1 | |
| SCHEMBL19260661 | 0.78 | SRC (0.57) | EHMT2CYP2D6CYP2C19ACP1SRC | |
| SCHEMBL30367647 | 0.78 | TLR8 (0.63) | EHMT2EHMT1CYP2D6CYP2C19ACP1 | |
| SCHEMBL19260819 | 0.76 | CACNA2D1 (0.59) | EHMT2CYP2D6CYP2C19ACP1SRC | |
| SCHEMBL19260592 | 0.76 | SRC (0.56) | EHMT2CYP2D6CYP2C19ACP1SRC | |
| Acridine SCHEMBL28069353 | 0.75 | SLC2A1 (0.52) | HRH3ALDH1A1KDM4EL3MBTL1LMNA | |
| Acridine SCHEMBL29277654 | 0.74 | SLC2A1 (0.51) | HRH3ALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254651-B2 | Histone methyltransferase inhibitors | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2022-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11254651-B2 | Histone methyltransferase inhibitors | EHMT1, EHMT2, BMI1 | EHMT2 2/4885EHMT1 1/4885CYP2D6 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.