Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.58 |
| ▸ | DPP4 | P27487 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16368739 | 0.85 | ALDH1A1 (0.61) | EPHX2DPP4MEN1ALDH1A1KMT2A | |
| SCHEMBL15247300 | 0.85 | EPHX2 (0.58) | EPHX2DPP4MEN1ALDH1A1KMT2A | |
| SCHEMBL16435174 | 0.85 | ALDH1A1 (0.61) | EPHX2DPP4MEN1ALDH1A1KMT2A | |
| SCHEMBL22874720 | 0.85 | EPHX2 (0.58) | EPHX2DPP4MEN1ALDH1A1KMT2A | |
| SCHEMBL15155982 | 0.83 | EPHX2 (0.56) | EPHX2DPP4MEN1ALDH1A1KMT2A | |
| SCHEMBL22875196 | 0.83 | EPHX2 (0.70) | EPHX2MEN1ALDH1A1KMT2A | |
| SCHEMBL17114639 | 0.83 | EPHX2 (0.56) | EPHX2DPP4MEN1ALDH1A1KMT2A | |
| SCHEMBL23118866 | 0.82 | DPP4 (0.48) | EPHX2DPP4MEN1ALDH1A1KMT2A | |
| SCHEMBL23049149 | 0.81 | DPP4 (0.47) | EPHX2DPP4MEN1KMT2A | |
| SCHEMBL12351445 | 0.81 | DPP4 (0.47) | EPHX2DPP4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240293362-A1 | Soluble Epoxide Hydrolase Inhibitors and Use Thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2024-09-05 | — | — | US | disclosed |
| WO-2023064370-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND USE THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2023-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240293362-A1 | Soluble Epoxide Hydrolase Inhibitors and Use Thereof | EPHX1, EPHX2, NCEH1 | EPHX2 2/4885DPP4 1270/4885MEN1 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.