SCHEMBL30368256

SCHEMBL30368256

CCCC=CC(CCCCCC)OC(C)=O

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GALR3 O60755 1/20 0.47
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
PDE4D Q08499 4/20 0.43
GLS2 Q9UI32 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29259205 0.94 MEN1 (0.50) GALR3MEN1KMT2APDE4D
SCHEMBL17633873 0.89 GALR3 (0.42) GALR3MEN1KMT2APDE4D
SCHEMBL17633875 0.89 GALR3 (0.42) GALR3MEN1KMT2APDE4D
SCHEMBL500452 0.87 MEN1 (0.46) MEN1KMT2APDE4D
SCHEMBL500451 0.87 MEN1 (0.46) MEN1KMT2APDE4D
SCHEMBL29094957 0.87 MEN1 (0.45) GALR3MEN1KMT2APDE4D
SCHEMBL11087291 0.86 ALDH1A1 (0.45) GALR3MEN1KMT2APDE4D
SCHEMBL11411941 0.84 GALR3 (0.40) GALR3MEN1KMT2APDE4D
SCHEMBL11411944 0.84 GALR3 (0.40) GALR3MEN1KMT2APDE4D
SCHEMBL11513669 0.84 PDE4D (0.43) GALR3MEN1KMT2APDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116096752-A anti-BCMA antibody-drug conjugates and methods of use thereof 卫材R&D管理有限公司 2023-05-09 CN disclosed