Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23511690 | 0.91 | HPGD (0.66) | HPGDKDM4EMAPTTDP1L3MBTL1 | |
| SCHEMBL27690326 | 0.89 | HPGD (0.64) | HPGDKDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL873994 | 0.85 | HPGD (0.72) | HPGDKDM4EMAPTTDP1L3MBTL1 | |
| SCHEMBL29083645 | 0.84 | MAPT (0.52) | HPGDKDM4EMKNK1MKNK2MAPT | |
| SCHEMBL11270838 | 0.83 | KDM4E (0.65) | HPGDKDM4EMAPTCYP2C19HSD17B10 | |
| SCHEMBL3029776 | 0.82 | MKNK1 (0.63) | MKNK1MKNK2SIRT2CHEK2 | |
| SCHEMBL133668 | 0.81 | KDM4E (0.67) | HPGDKDM4EMAPTCYP2C19HSD17B10 | |
| SCHEMBL11682285 | 0.79 | KDM4E (0.65) | HPGDKDM4EMAPTCYP2C19HSD17B10 | |
| SCHEMBL28828108 | 0.79 | KDM4E (0.65) | HPGDKDM4EMAPTCYP2C19HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL11681866 | 0.79 | KDM4E (0.65) | HPGDKDM4EMAPTCYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216796-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | KATTAR SOLOMON | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216796-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | BRDT, AADAC, ACIN1 | HPGD 188/4885KDM4E 295/4885MKNK1 3440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.