Sugi Predict

Sugi Predict / Targets / ACIN1

ACIN1

Apoptotic chromatin condensation inducer in the nucleus · Q9UKV3 · ACIN1 on Sugi Atlas →

0 patent compounds predicted against ACIN1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to ACIN1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Compared the Efficacy and Safety of CDOP Combined With Chidamide and CDOP in de Novo Peripheral T Cell Lymphoma Patients PHASE3UNKNOWN
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Vorinostat in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma PHASE2COMPLETED
Chidamide Combined With Toripalimab in Sarcoma PHASE2COMPLETED
LBH589 Treatment for Refractory Clear Cell Renal Carcinoma PHASE2COMPLETED
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma PHASE1/PHASE2COMPLETED
Vorinostat in Children PHASE1/PHASE2COMPLETED
BAY 43-9006 (Sorafenib) to Treat Relapsed Non-Small Cell Lung Cancer PHASE2COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma PHASE1WITHDRAWN
A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancers PHASE1COMPLETED
Vorinostat in Treating Women With Ductal Carcinoma in Situ of the Breast PHASE1COMPLETED
Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion With or Without Concurrent Celecoxib in Subjects With Pulmonary and Pleural Malignancies PHASE1COMPLETED
Methotrexate Alone vs Combination With Excimer Light in Nail Psoriasis nanUNKNOWN
Harvest of CTCs From MBC Patients Using the Parsortix™ PC1 System nanCOMPLETED
Chi-GVM Regimen for the Treatment of R/R PTCL nanUNKNOWN
Circulating Markers for Ischemic Heart Disease nanRECRUITING
The Effect of Vitamin E-coated Polysulfone Membrane on Oxidative Stress, Inflammation and Monocytes in Critically Ill Patients in CRRT nanUNKNOWN
Inhibition of Che-1/AATF as a New Tool in Multiple Myeloma Treatment nanUNKNOWN
Effect of the Incoportation of Copper and Zinc Nanoparticles Into Dental Adhesives nanUNKNOWN
Cell Membrane Potential Regulates Spatial-Specific Mechanoptosis Resistance and Metastasis in Colorectal Cancer Via Mechanotransduction and the PVR/CD96 Axis nanCOMPLETED
Apoptosis Markers in Aggressive Periodontitis nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Regulation of Vitamin D Receptor (VDR),Calcium Sensing Receptor (CaSR), Cyclin D1,Ki67 and Proliferating Cell Nuclear Antigen (PCNA) in Primary Hyperparathyroidism nanUNKNOWN
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma nanUNKNOWN
Role of ADA SNPs in Subjects With Relapsing Multiple Sclerosis (RMS) nanUNKNOWN
Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility nanRECRUITING
Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients nanACTIVE_NOT_RECRUITING
Interest of the Sialendoscopy Associated With a Local Injection of Corticosteroids in the Treatment of Radio-induced Xerostomia in Comparison With the Hygiene Rules nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a ACIN1 binder may also engage these)

ProteinNameSimilarity
Q9JIX8 — 1.000 Q9JIX8 →
Q8BZ32 — 0.993 Q8BZ32 →
Q63755 — 0.992 Q63755 →
Q9JL04 — 0.992 Q9JL04 →
Q3T0A6 — 0.991 Q3T0A6 →
O54963 — 0.990 O54963 →
P19332 — 0.990 P19332 →
A6X8Z5 — 0.990 A6X8Z5 →
Q80YR5 — 0.990 Q80YR5 →
D6RIA3 — 0.990 D6RIA3 →
Q6P9P0 — 0.990 Q6P9P0 →
Q5S6V2 — 0.990 Q5S6V2 →
Q5YCW1 — 0.989 Q5YCW1 →
Q5YCW0 — 0.989 Q5YCW0 →
Q6NWJ0 — 0.989 Q6NWJ0 →
MAPT Microtubule-associated protein tau 0.989 landscape →
A6H5Y1 — 0.989 A6H5Y1 →
Q3UMU9 — 0.989 Q3UMU9 →
KDM3B Lysine-specific demethylase 3B 0.988 landscape →
Q8C5W0 — 0.988 Q8C5W0 →
Q8NCN4 — 0.988 Q8NCN4 →
Q5YCV9 — 0.988 Q5YCV9 →
O46385 — 0.988 O46385 →
PHF20 PHD finger protein 20 0.988 landscape →
Q99L02 — 0.988 Q99L02 →
Q7YQM2 — 0.988 Q7YQM2 →
TET3 Methylcytosine dioxygenase TET3 0.988 landscape →
Q924C5 — 0.988 Q924C5 →
Q76N89 — 0.988 Q76N89 →
Q8K0T0 — 0.988 Q8K0T0 →