Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 7/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.59 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26186466 | 1.00 | MAPK10 (0.69) | MAPK10KCNH2SCN5ASCN9AMAPK14 | |
| SCHEMBL4665722 | 0.87 | KCNH2 (0.64) | MAPK10KCNH2SCN5ASCN9AMAPK14 | |
| SCHEMBL1518968 | 0.81 | MAPK10 (1.00) | MAPK10KCNH2MAPK14MAPK1MEN1 | |
| SCHEMBL30216764 | 0.81 | KCNH2 (0.58) | MAPK10KCNH2SCN5ASCN9AMAPK1 | |
| SCHEMBL23588551 | 0.81 | KCNH2 (0.58) | MAPK10KCNH2SCN5ASCN9AMAPK1 | |
| SCHEMBL24010544 | 0.81 | KCNH2 (0.58) | MAPK10KCNH2SCN5ASCN9AMAPK14 | |
| SCHEMBL6829712 | 0.81 | MAPK10 (0.84) | MAPK10KCNH2SCN5ASCN9AMAPK14 | |
| SCHEMBL1136895 | 0.78 | MET (0.55) | MAPK10KCNH2SCN5ASCN9AMAPK14 | |
| SCHEMBL24173476 | 0.77 | MAPK10 (0.67) | MAPK10MAPK14MAPK1MEN1KMT2A | |
| SCHEMBL374096 | 0.76 | CDK5 (0.61) | MAPK10KCNH2SCN5ASCN9AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4171744-A1 | USE OF N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY FOR TREATING CERTAIN OCULAR DISORDERS | Bayer Aktiengesellschaft (DE) | 2023-05-03 | — | — | EP | disclosed |
| EP-4172146-A1 | SUBSTITUTED N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY | Bayer Aktiengesellschaft (DE) | 2023-05-03 | — | — | EP | disclosed |