SCHEMBL30368484

SCHEMBL30368484

Cc1ccc(C2CC(=O)CC(=O)C2)cc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.47
MAPT P10636 2/20 0.47
TP53 P04637 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.37
ABCC9 O60706 3/20 0.36
KCNJ11 Q14654 3/20 0.36
ABCC8 Q09428 1/20 0.36
KCNJ8 Q15842 1/20 0.36
RECQL P46063 1/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HPGD P15428 3/20 0.34
TSHR P16473 1/20 0.33
BRD4 O60885 1/20 0.33
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25374084 0.87 GAA (0.37) GAAMAPTTP53L3MBTL1ABCC9
SCHEMBL25375225 0.85 GAA (0.36) GAAMAPTTP53L3MBTL1ABCC9
SCHEMBL13454021 0.84 MAPT (0.52) GAAMAPTTP53L3MBTL1RECQL
SCHEMBL29496819 0.84 MAPT (0.52) GAAMAPTTP53L3MBTL1RECQL
SCHEMBL30368131 0.79 SLC6A2 (0.49) GAAMAPTTP53L3MBTL1RECQL
SCHEMBL5482494 0.79 MAPT (0.47) GAAMAPTTP53L3MBTL1RECQL
SCHEMBL25375025 0.79 PDE4A (0.46) GAAMAPTPOLBKMT2AHPGD
SCHEMBL30368709 0.79 PDE4A (0.46) GAAMAPTPOLBKMT2AHPGD
SCHEMBL26601672 0.79 POLB (0.39) GAAMAPTTP53POLBKMT2A
SCHEMBL11832979 0.76 MAPT (0.47) GAAMAPTTP53L3MBTL1ABCC9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509579-B2 Thermoplastic resin and optical lens including same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-12-30 US disclosed
CN-115996931-B Cyclic diol compound, process for producing the compound, and use of the compound 新日本理化株式会社 2025-04-01 CN disclosed
US-20230399510-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-14 US disclosed
EP-4239010-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-09-06 EP disclosed
CN-116323753-A Thermoplastic resin and optical lens comprising the same 三菱瓦斯化学株式会社 2023-06-23 CN disclosed
CN-115996931-A Cyclic diol compound, process for producing the compound, and use of the compound 新日本理化株式会社 2023-04-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509579-B2 Thermoplastic resin and optical lens including same RIF1, POT1, LAS1L GAA 921/4885MAPT 932/4885TP53 2807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.