Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317215 | 0.78 | NPC1 (0.45) | TSHRMAPK1HPGDALDH1A1NPSR1 | |
| SCHEMBL8048066 | 0.75 | ALDH1A1 (0.49) | TSHRMAPK1HPGDUSP2ALDH1A1 | |
| SCHEMBL31254129 | 0.71 | ASAH1 (0.43) | MAPK1ALDH1A1 | |
| SCHEMBL31334529 | 0.70 | ASAH1 (0.44) | — | |
| SCHEMBL23832563 | 0.69 | ALDH1A1 (0.41) | TSHRALDH1A1LMNA | |
| SCHEMBL3864406 | 0.69 | TSHR (0.45) | TSHRMAPK1HPGDUSP2ALDH1A1 | |
| SCHEMBL9410541 | 0.69 | MAPK1 (0.57) | TSHRMAPK1HPGDUSP2ALDH1A1 | |
| SCHEMBL3447171 | 0.69 | MAPK1 (0.57) | TSHRMAPK1HPGDUSP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30509213 | 0.68 | ALDH1A1 (0.41) | TSHRALDH1A1LMNA | |
| SCHEMBL31437095 | 0.68 | HTR2C (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697989-A | Tropomyosin Receptor Kinase (TRK) degrading compounds and methods of use | 上海睿跃生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |