SCHEMBL30368744

SCHEMBL30368744

Oc1cncc2[nH]ccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.45
PIK3C3 Q8NEB9 2/20 0.38
KDM5A P29375 1/20 0.38
IGF1R P08069 1/20 0.37
CDK2 P24941 1/20 0.37
DYRK1B Q9Y463 1/20 0.37
PIK3CD O00329 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
PARP1 P09874 1/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
BLM P54132 1/20 0.34
PARP15 Q460N3 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PRMT5 O14744 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23937722 1.00 BRD4 (0.45) BRD4PIK3C3KDM5AIGF1RCDK2
SCHEMBL30578263 0.74 BRD4 (0.41) BRD4PIK3C3IGF1RCDK2DYRK1B
SCHEMBL2619221 0.74 BRD4 (0.45) BRD4PIK3C3IGF1RCDK2DYRK1B
SCHEMBL1019760 0.74 NFATC1 (0.44) BRD4PIK3C3IGF1RCDK2DYRK1B
SCHEMBL23148015 0.74 NUDT1 (0.43) BRD4PIK3C3IGF1RCDK2DYRK1B
SCHEMBL2628872 0.74 BRD4 (0.41) BRD4PIK3C3IGF1RCDK2DYRK1B
SCHEMBL30554075 0.74 NFATC1 (0.44) BRD4PIK3C3IGF1RCDK2DYRK1B
SCHEMBL15926855 0.74 BRD4 (0.41) BRD4PIK3C3IGF1RCDK2DYRK1B
SCHEMBL529739 0.74 AHR (0.52) BRD4PIK3C3IGF1RCDK2DYRK1B
SCHEMBL1472503 0.74 BRD4 (0.39) BRD4PIK3C3IGF1RCDK2DYRK1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4440573-A1 NOVEL AZA-SUBSTITUTED PSILOCIN ANALOGS AND METHODS OF SYNTHESIZING THE SAME Mydecine Innovations Group Inc. (US) 2024-10-09 EP disclosed
WO-2023101722-A1 NOVEL AZA-SUBSTITUTED PSILOCIN ANALOGS AND METHODS OF SYNTHESIZING THE SAME MEDECINE INNOVATIONS GROUP INC. (US) 2023-06-08 WO disclosed