Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 9/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29016638 | 1.00 | GPR52 (0.43) | GPR52CSNK1DESR1ESR2LIPG | |
| SCHEMBL30370521 | 0.82 | CSNK1D (0.40) | CSNK1DESR1ESR2TRPV1AKR1B1 | |
| SCHEMBL29016676 | 0.82 | CSNK1D (0.40) | CSNK1DESR1ESR2TRPV1AKR1B1 | |
| SCHEMBL29016639 | 0.81 | CSNK1D (0.40) | CSNK1DNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30370383 | 0.81 | CSNK1D (0.40) | CSNK1DNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30370117 | 0.80 | GPR52 (0.54) | GPR52CSNK1DLIPGTRPV1NPC1 | |
| SCHEMBL29016605 | 0.80 | GPR52 (0.54) | GPR52CSNK1DLIPGTRPV1NPC1 | |
| SCHEMBL28984539 | 0.77 | CSNK1D (0.56) | CSNK1DAKR1B1 | |
| SCHEMBL30306727 | 0.77 | CSNK1D (0.56) | CSNK1DAKR1B1 | |
| SCHEMBL30370452 | 0.77 | EPHX2 (0.48) | GPR52CSNK1DTRPV1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |